UpToDate is a comprehensive, evidence-based medicine resource, prepared for physicians to get a brief and practical answer to the asked questions. Information is updated every 4 months, however, if there are some crucial changes, the text is updated immediately.The texts indexed in the database are reviewed.
The database is created with cooperation of 4,000 prominent international specialists and contains over 10,000 clinical issues across 20 specialties.
UpToDate:

gives access to the most current knowledge from the chosen medical specialty

helps to make a decision in terms of diagnosis and treatment, includes information about effectiveness, posology (dosage) and interaction of particular drugs